The first sign of this deficiency is usually gums that bleed when the teeth are brushed. Other signs of abnormal bleeding, such as ecchymosis, epistaxis, and hematuria, may occur. GI bleeding may produce hematemesis and melena; intracranial bleeding may cause decreased level of consciousness and focal neurological deficits.
(info - Professional Guide to Signs & Symptoms 5th Edition -Lippincott Williams & Wilkins)
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